Sucralose
Also: Splenda · E955 · trichlorogalactosucrose
Probably fine occasionally — the gut microbiome data is concerning enough to avoid daily use, especially in pre-workout taken on an empty stomach.
Testosterone & hormonal load
Sucralose does not have established direct testosterone effects in humans. The concern is indirect: sucralose alters gut microbiome composition, which influences gut barrier integrity, inflammation, and potentially metabolic hormone signaling. Some human studies show a glucose response alteration when sucralose is consumed before a glucose load. Direct testosterone effects are not demonstrated in human studies.
Found in.
Two jurisdictions, two different verdicts.
Approved sweetener E955 with ADI of 15 mg/kg body weight per day (EFSA).
GRAS. Acceptable daily intake set at 5 mg/kg body weight/day. Approved in 1998.
The receipts.
- [01]Suez et al. 2014 — Artificial sweeteners and gut microbiome (PubMed)pubmed.ncbi.nlm.nih.gov/25231862/
- [02]Schiffman & Rother 2013 — Sucralose, a synthetic organochlorine sweetener: overview of biological issues (PubMed)pubmed.ncbi.nlm.nih.gov/24219506/
- [03]FDA — Sucralose GRAS noticewww.fda.gov/food/food-additives-petitions/high-intensity-sweeteners
Find Sucralose before it finds you.
Point the camera at any barcode. Mangood reads the ingredient list and tells you, in one tap, whether Sucralose is hiding in the bottle in your hand.