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Ingredient dossier · No. 031

Ashwagandha

Also: Withania somnifera · Indian ginseng · KSM-66 · Sensoril · winter cherry


Solid choiceone of the few 'T-booster' ingredients with consistent RCT support for modest testosterone and recovery benefits.


01 · Hormonal impact

Testosterone & hormonal load

Evidence
ModerateAnimal studies with mechanistic evidence

Multiple randomized controlled trials using standardized ashwagandha root extracts (particularly KSM-66 and Sensoril) show modest but consistent increases in total testosterone (approximately 10–22%) in men, alongside significant reductions in cortisol. The proposed mechanism involves HPA-axis modulation: lower cortisol reduces cortisol-induced suppression of Leydig cell testosterone synthesis. The evidence is stronger than most other marketed 'T-boosters.'


02 · Where it appears

Found in.

01Standalone ashwagandha capsules
02Testosterone booster formulas
03Sleep and recovery supplements
04Adaptogen blends
05Nootropic stacks

03 · The regulators

Two jurisdictions, two different verdicts.

European Union

Sold as a food supplement in EU. Not an approved medicinal herb under THMPD. No safety restrictions at common supplement doses.

United States · FDA

Dietary supplement ingredient under DSHEA. GRAS status not formally established; considered safe at typical supplement doses.


04 · Sources

The receipts.

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