Diethyl Phthalate (DEP)
Also: DEP · phthalic acid diethyl ester · diethyl benzene-1,2-dicarboxylate
Avoid — the most common phthalate in men's fragranced products and a confirmed anti-androgen in animal models.
Testosterone & hormonal load
DEP is the phthalate most commonly found in fragranced personal care products. It shows anti-androgenic activity in animal models and is detectable in the urine of nearly all men in the US. While its human evidence is weaker than DEHP or DBP, cumulative exposure through daily grooming products is a realistic concern.
Found in.
Two jurisdictions, two different verdicts.
Not currently restricted in cosmetics but classified as an endocrine disruptor of concern under the EU ED strategy. Under SVHC assessment.
No restriction in cosmetics. CDC NHANES data shows widespread population exposure.
The receipts.
- [01]Weaver et al. 2020 — DEP exposure animal toxicology systematic review (PubMed)pubmed.ncbi.nlm.nih.gov/32958228/
- [02]ATSDR — Diethyl phthalate toxic substance portalwwwn.cdc.gov/TSP/substances/ToxSubstance.aspx?toxid=112
- [03]CDC — National Exposure Report biomonitoring datawww.cdc.gov/biomonitoring/resources/national-exposure-report.html
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