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Ingredient dossier · No. 016

Quaternium-15

Also: Dowicil 200 · 1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride · formaldehyde releaser


Avoidformaldehyde-releasing preservative banned in EU cosmetics since 2023; one of the highest-potency formaldehyde releasers in personal care.


01 · Hormonal impact

Testosterone & hormonal load

Evidence
WeakIn vitro only or single study

Quaternium-15 releases formaldehyde as its primary antimicrobial mechanism — releasing more formaldehyde per weight than most other formaldehyde-releasing preservatives. The EU banned quaternium-15 in cosmetics from 2023 (EU Regulation 2023/1545) due to formaldehyde carcinogenicity and allergenicity concerns. Formaldehyde has reproductive toxicity at occupational exposure levels; daily scalp or skin exposure represents repeated low-level exposure.


02 · Where it appears

Found in.

01Shampoo
02Body wash
03Hair styling products
04Facial cleanser
05Liquid hand soap

03 · The regulators

Two jurisdictions, two different verdicts.

European Union

Banned in all cosmetics from December 2023 under EU Regulation 2023/1545.

United States · FDA

Permitted in US cosmetics. No specific concentration limit.


04 · Sources

The receipts.

  1. [01]
    EU Regulation 2023/1545 — Quaternium-15 ban in cosmetics
    eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:32023R1545
  2. [02]
    ACDS — Quaternium-15 Allergen of the Year 2005
    www.contactderm.org/i4a/pages/index.cfm?pageID=3465
  3. [03]
    IARC Monographs Vol. 88 — Formaldehyde
    publications.iarc.who.int/Book-And-Report-Series/Iarc-Monographs-On-The-Identification-Of-Carcinogenic-Hazards-To-Humans/Formaldehyde-2-Butoxyethanol-And-1--Em-Tert-Em--Butoxypropan-2-ol-2006

05 · Related dossiers
01DMDM HydantoinD · 20
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