Triclocarban
Also: TCC · 3,4,4'-trichlorocarbanilide · 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea
Avoid — banned by FDA in OTC soaps in 2016; amplifies androgen signaling abnormally and is environmentally persistent.
Testosterone & hormonal load
Triclocarban does not block testosterone — instead it amplifies androgen receptor signaling abnormally in cell studies, and may increase endogenous testosterone effects to supra-physiological levels. This androgen potentiation is considered an endocrine disruption concern. It was banned from consumer antiseptic soaps alongside triclosan and is environmentally persistent, bioaccumulating in aquatic organisms.
Found in.
Two jurisdictions, two different verdicts.
Not permitted in cosmetics.
Banned in consumer antiseptic wash products (2016 final rule, 21 CFR 310).
The receipts.
- [01]FDA — Antibacterial soaps final rule overviewwww.fda.gov/consumers/consumer-updates/antibacterial-soap-you-can-skip-it-use-plain-soap-and-water
- [02]Chen et al. 2008 — Triclocarban enhances testosterone action (PubMed)pubmed.ncbi.nlm.nih.gov/18048496/
- [03]Yueh et al. 2012 — Triclocarban activates CAR and estrogen receptor alpha (PubMed)pubmed.ncbi.nlm.nih.gov/22761658/
Find Triclocarban before it finds you.
Point the camera at any barcode. Mangood reads the ingredient list and tells you, in one tap, whether Triclocarban is hiding in the bottle in your hand.