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Ingredient dossier · No. 038

Boron

Also: boric acid · sodium borate · boron citrate · calcium fructoborate


Cheap and worth tryingsmall but consistent free testosterone effect via SHBG reduction; well-tolerated at 6–10 mg/day.


01 · Hormonal impact

Testosterone & hormonal load

Evidence
ModerateAnimal studies with mechanistic evidence

A small but well-designed human study (Naghii et al. 2011) found that 6 mg/day boron for 1 week significantly increased free testosterone by 28%, reduced SHBG by 9%, and decreased estradiol by 39% in healthy men. Boron appears to reduce SHBG, the protein that binds testosterone and renders it biologically unavailable, thereby increasing the free fraction. The effect size is modest but consistent across the limited literature.


02 · Where it appears

Found in.

01Testosterone booster blends
02Men's multivitamins
03Bone health supplements

03 · The regulators

Two jurisdictions, two different verdicts.

European Union

Permitted in food supplements. EFSA guidance dose: up to 10 mg/day. Higher doses may cause reproductive toxicity in animal studies.

United States · FDA

Not an essential nutrient with an established RDA. Sold as a dietary supplement under DSHEA. Upper tolerable intake level: 20 mg/day (Institute of Medicine).


04 · Sources

The receipts.

  1. [01]
  2. [02]
  3. [03]
    EFSA — Boron tolerable upper intake level
    efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2004.99

05 · Related dossiers
01ZincB · 7802Vitamin D3 (Cholecalciferol)A · 8803MagnesiumB · 76
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