Vitamin D3 (Cholecalciferol)
Also: cholecalciferol · vitamin D · 25(OH)D · calciferol
Take it if you're deficient — one of the most replicable links between a vitamin and testosterone; check serum 25(OH)D first.
Testosterone & hormonal load
Vitamin D receptors (VDR) are present in Leydig cells and are required for normal testosterone synthesis. Observational studies consistently show that men with lower 25(OH)D have lower testosterone levels. Multiple RCTs in deficient men show that vitamin D3 supplementation (2,000–5,000 IU/day) increases testosterone by 20–25%. The effect is most pronounced in men with baseline 25(OH)D below 20 ng/mL. Supplementation in replete men shows smaller or negligible effects.
Found in.
Two jurisdictions, two different verdicts.
Permitted in food supplements at up to 100 μg (4,000 IU) per daily serving under EFSA guidance. Upper intake level 100 μg/day.
Dietary supplement ingredient under DSHEA. Tolerable upper intake level: 4,000 IU/day (NIH), though many clinicians use higher supervised doses.
The receipts.
- [01]Pilz et al. 2011 — Vitamin D3 and testosterone RCT (PubMed)pubmed.ncbi.nlm.nih.gov/21154195/
- [02]Wehr et al. 2010 — Association of vitamin D status with serum androgen levels in men (PubMed)pubmed.ncbi.nlm.nih.gov/20050857/
- [03]Endocrine Society — Clinical Practice Guideline on Vitamin Dacademic.oup.com/jcem/article/96/7/1911/2833671
Find Vitamin D3 (Cholecalciferol) before it finds you.
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