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Ingredient dossier · No. 034

D-Aspartic Acid (DAA)

Also: DAA · D-aspartate · sodium D-aspartate · d-aspartic acid


Largely overhypedinitial testosterone-boosting studies didn't replicate in trained men, and high doses may backfire.


01 · Hormonal impact

Testosterone & hormonal load

Evidence
WeakIn vitro only or single study

D-aspartic acid is an amino acid involved in the hypothalamic-pituitary release of LH and in testosterone synthesis in the testes. An initial 2009 study in untrained men showed a 33% testosterone increase over 12 days. However, multiple subsequent well-controlled trials in resistance-trained men found no significant testosterone change, and one trial found a significant decrease at 6g/day. The compound appears ineffective for men with already-adequate testosterone levels.


02 · Where it appears

Found in.

01Testosterone booster formulas
02Standalone DAA powders and capsules
03Pre-workout supplements

03 · The regulators

Two jurisdictions, two different verdicts.

European Union

Sold as a food supplement amino acid in EU. No specific restrictions.

United States · FDA

Dietary supplement ingredient under DSHEA. No clinical guidance.


04 · Sources

The receipts.

  1. [01]
  2. [02]
  3. [03]

05 · Related dossiers
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